This paper explains and evaluates the effects of the developing crisis on the mobility of third-country nationals in Greece and other South European political economies. In doing so it explores the mobility of these migrants within the context of the informal economic activity in which many such migrants have been involved. The paper exposes the distance separating the law and the actual enforcement of fundamental employment- and mobility-related rights of irregular migrants in Greece and other southern European countries. It identifies the significance of the familistic welfare regime of the European South in framing migrants’ characteristics and their consequent mobility in the region. The article argues that the familistic welfare regime of the host country is inextricably linked to migrants’ employment trajectories and fundamentally affects the strategies that migrants have developed in order to protect themselves in lieu of effective rights regulation.